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Strategies to Reduce Risk of Ovarian and Breast Cancer

22/Sep/2006: A new research has given hope to women with certain genetic mutations to lower the risks of ovarian cancer by removing their ovaries.

A team of international researchers who conducted a study on a group of women who have certain genetic mutations, have confirmed that their study shows that women with genetic mutations (known as BRCA mutation) who had their ovaries removed reduced their risk of cancer by 80% even though 7% still developed the disease after the procedure which is known as oophorectomy.

The study was conducted on 1,828 women with genetic mutations from Canada, the US, Europe and Israel by Dr. Steven Narod, a Canada Research Chair in Breast Cancer and professor of public health sciences at the Center for Research in Women’s Health in Toronto.

Out of these 1,828 women, 555 of them already had their ovaries and fallopian tubes removed, 490 of them had them removed when the study was conducted and 783 of them did not undergo the procedure at all.

32 cases of ovarian cancer were found in the women who did not undergo the procedure whilst 7 women still got the disease after the procedure.

Dr. Jay Brooks, chairman of hematology/oncology at the Ochsner Clinic Health System in Baton Rouge, LA said "If you have a BRCA mutation, and you have not had your ovaries and uterus removed, they need to be removed once you have completed childbearing.

It's the single greatest thing to do to reduce ovarian-cancer risk, and it reduces the risk of breast cancer, too."

In a another study on more than 87,000 postmenopausal women in the Nurses’ Health Study by Heather Eliassen, an instructor in medicine at Brigham and Women’s Hospital and Harvard School of Medicine and Public Health in Boston also reveals that the risk of breast cancer can be reduced by losing weight after menopause.

The results of these studies can be found in the July 12 issue of Journal of the American Medical Association.
Researchers have confirmed that 15% of the breast cancer cases were due to regular weight gain of about 2kgs or more since the age of 18.

Women who manage to reduce 22 pounds or more after menopause and maintain their weight can reduce the risk of breast cancer by almost 60%.

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